Gene

adamts12

ID
ZDB-GENE-070705-471
Name
ADAM metallopeptidase with thrombospondin type 1 motif, 12
Symbol
adamts12 Nomenclature History
Previous Names
  • si:dkey-43l20.2
  • unm_sa1731
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular region. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and thymus. Orthologous to human ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Brunet et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adamts12 Human Ortholog
No data available
Associated With adamts12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR006586 ADAM, cysteine-rich domain
Domain IPR010294 ADAM-TS Spacer 1
Domain IPR010909 PLAC
Domain IPR041645 ADAM cysteine-rich domain 2
Family IPR013273 ADAMTS/ADAMTS-like
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length ADAM, cysteine-rich domain ADAM cysteine-rich domain 2 ADAMTS/ADAMTS-like ADAM-TS Spacer 1 Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, propeptide PLAC Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:F1R8A1 1500
UniProtKB:A0A2R8Q141 200
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations