Gene
kmt2cb
- ID
- ZDB-GENE-070705-340
- Name
- lysine (K)-specific methyltransferase 2Cb
- Symbol
- kmt2cb Nomenclature History
- Previous Names
-
- mll3b
- si:dkey-193e13.2
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have histone binding activity; histone methyltransferase activity (H3-K4 specific); and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to MLL3/4 complex. Human ortholog(s) of this gene implicated in Kleefstra syndrome 2; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human KMT2C (lysine methyltransferase 2C).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Sun et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Kleefstra syndrome 2 | Alliance | Kleefstra syndrome 2 | 617768 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein | Length |
---|---|
UniProtKB:A0A8M3AWQ1
|
4854 |
UniProtKB:A0A8M6Z169
|
4853 |
UniProtKB:A0A8M3AP79
|
4841 |
UniProtKB:A0A8M6Z161
|
4891 |
UniProtKB:A0A8M3APU4
|
4876 |
UniProtKB:A0A8M6YVA2
|
4891 |
UniProtKB:A0A8M3B7B2
|
4892 |
UniProtKB:A0A8M2BAF3
|
4891 |
UniProtKB:A0A8M2BAH2
|
4880 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
kmt2cb-201
(1)
|
17074 nt |
Interactions and Pathways
No data available
Plasmids
No data available