Gene
epg5
- ID
- ZDB-GENE-070705-307
- Name
- ectopic P-granules autophagy protein 5 homolog (C. elegans)
- Symbol
- epg5 Nomenclature History
- Previous Names
-
- si:dkey-165i4.3
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Involved in autophagosome-lysosome fusion; intestinal epithelial cell development; and intestinal stem cell homeostasis. Is expressed in several structures, including blastodisc; liver; oral cavity; pleuroperitoneal region; and unfertilized egg. Used to study Vici syndrome. Human ortholog(s) of this gene implicated in Vici syndrome. Orthologous to human EPG5 (ectopic P-granules autophagy protein 5 homolog).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Meneghetti et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Vici syndrome | Alliance | Vici syndrome | 242840 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
Vici syndrome | epg5ia31/ia31 | standard conditions | Meneghetti et al., 2019 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Family | IPR051436 | Autophagy-related EPG5 |
Domain Details Per Protein
Protein | Length | Autophagy-related EPG5 |
---|---|---|
UniProtKB:A5WUT8
|
||
UniProtKB:A0A8M3ASP3
|
2546 | |
UniProtKB:A0A8M2BCV4
|
2548 |
Interactions and Pathways
No data available
Plasmids
No data available