Gene

arhgef9a

ID
ZDB-GENE-070705-271
Name
Cdc42 guanine nucleotide exchange factor (GEF) 9a
Symbol
arhgef9a Nomenclature History
Previous Names
  • si:ch73-92i20.3
  • si:cu137718.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Predicted to localize to cytoplasm and postsynaptic density. Is expressed in retinal ganglion cell layer. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 8. Orthologous to human ARHGEF9 (Cdc42 guanine nucleotide exchange factor 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arhgef9a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 8 Alliance Developmental and epileptic encephalopathy 8 300607
Associated With arhgef9a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001452 SH3 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR035728 Rho guanine nucleotide exchange factor 9, SH3 domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length Dbl homology (DH) domain Dbl homology (DH) domain superfamily PH-like domain superfamily Pleckstrin homology domain Rho guanine nucleotide exchange factor 9, SH3 domain SH3 domain SH3-like domain superfamily
UniProtKB:A0A2R8Q4X7 516
UniProtKB:E9QHS5 549
UniProtKB:A0A1Q1NKP8 521
UniProtKB:E9QEP1 250
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations