ZFIN ID: ZDB-GENE-070702-4
Gene Name: apolipoprotein Ba
Gene Symbol: apoba
Previous Names: apob (1), im:6911942, wu:fb30e06, zmp:0000000614 (1)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 5 publications
Directly Submitted Expression Data: 5 figures (4 images) from Thisse et al., 2004 [IMAGE:6911942]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  heart, liver, unspecified, whole organism (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa11961 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13626 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13822 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-apoba (1)
    PHENOTYPE
    Data: Fig. S3 from Avraham-Davidi et al., 2012
    Observed in: sprouting angiogenesis, subintestinal vein
    DISEASE ASSOCIATED WITH apoba HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Hypercholesterolemia, due to ligand-defective apo B 144010
    Hypobetalipoproteinemia 615558
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process cholesterol transport (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function lipid transporter activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001747 (1)
  • InterPro:IPR009454 (1)
  • InterPro:IPR011030 (1)
  • InterPro:IPR015255 (1)
  • InterPro:IPR015816 (1)
  • InterPro:IPR015817 (1)
  • InterPro:IPR015818 (1)
  • InterPro:IPR015819 (1)
  • PROSITE:PS51211 (1)
  • Pfam:PF01347 (1)
  • Pfam:PF06448 (1)
  • Pfam:PF09172 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoba-001 (1) 13486
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM apoba No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    apobaContained in: [BAC] CH211-117G17 (1) (order this)
    apobaEncodes: [EST] fb30e06, fc32g08, IMAGE:6911942 (1) (order this)
    apobaHas Artifact: [EST] fb79f11
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_689735 (1) 13478bp
    Genomic GenBank:BX072551 (1) 164264bp
    Select Tool
    Polypeptide UniProtKB:E7FBD3 (1) 4418aa
    Sequence Clusters UniGene:159522 (1)
    Sequence Information (all 22)
    OTHER apoba GENE PAGES 
  • Gene:566465 (1)
  • VEGA:OTTDARG00000038776 (1)
  • Ensembl(GRCz10):ENSDARG00000042780 (1)
  • ORTHOLOGY for apoba (Chr: 17) 
    Species Symbol Chromosome Accession # Evidence
    Human APOB 2
  • Gene:338
  • OMIM:107730
  • HGNC:603
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Mouse Apob 12
  • MGI:88052
  • Gene:238055
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (23)