header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-070702-4
Gene Name: apolipoprotein Ba
Gene Symbol: apoba    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: apob (1), im:6911942, wu:fb30e06, zmp:0000000614 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have lipid transporter activity. Predicted to be involved in cholesterol transport and triglyceride mobilization. Predicted to localize to the endoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Is expressed in heart; liver; and yolk syncytial layer. Orthologous to human APOB (apolipoprotein B).
Genome Resources: Alliance (1),  Gene:566465 (1),  Ensembl(GRCz11):ENSDARG00000042780 (2)
GENE EXPRESSION
All Expression Data: 13 figures from 7 publications
Directly Submitted Expression Data: 5 figures (4 images) from Thisse et al., 2004 [IMAGE:6911942]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6482 Point Mutation Unknown Premature Stop ENU
sa8678 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11961 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13626 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13822 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36449 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36450 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36451 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42959 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-apoba N/A 2
    DISEASE ASSOCIATED WITH apoba HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    familial hypobetalipoproteinemia 1 Alliance Hypobetalipoproteinemia 615558
    Hypercholesterolemia, familial, 2 144010
    DISEASE ASSOCIATED WITH apoba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cholesterol transport (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function lipid transporter activity (more)
    GO Terms (all 5)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA apoba-201 (1)    Ensembl 13486
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM apoba No data available
    MARKER RELATIONSHIPS
    apoba Contained in: [BAC] CH211-117G17 (1) (order this)
    apoba Encodes: [EST] fb30e06, fc32g08, IMAGE:6911942 (1) (order this)
    apoba Has Artifact: [EST] fb79f11
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_689735 (1) 12995 bp
    Genomic GenBank:BX072551 (1) 164264 bp
    Select Tool
    Polypeptide UniProtKB:E7FBD3 (1) 4418 aa
    Sequence Clusters UniGene:159522 (1)
    Sequence Information (all 23)
    ORTHOLOGY for apoba ( Chr: 17 )
    CITATIONS (37)