Gene

apoba

ID
ZDB-GENE-070702-4
Name
apolipoprotein Ba
Symbol
apoba Nomenclature History
Previous Names
  • apob (1)
  • im:6911942
  • wu:fb30e06
  • zmp:0000000614 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have lipid transporter activity. Predicted to be involved in cholesterol transport and triglyceride mobilization. Predicted to localize to endoplasmic reticulum. Is expressed in heart; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. S3 from Avraham-Davidi et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With apoba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial hypobetalipoproteinemia 1 Alliance Hypobetalipoproteinemia 615558
Hypercholesterolemia, familial, 2 144010
Associated With apoba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001747 Lipid transport protein, N-terminal
Domain IPR009454 Lipid transport, open beta-sheet
Domain IPR015255 Vitellinogen, open beta-sheet
Homologous_superfamily IPR011030 Lipovitellin-phosvitin complex, superhelical domain
Homologous_superfamily IPR015816 Vitellinogen, beta-sheet N-terminal
Homologous_superfamily IPR015819 Lipid transport protein, beta-sheet shell
Domain Details Per Protein
Protein Length Lipid transport, open beta-sheet Lipid transport protein, beta-sheet shell Lipid transport protein, N-terminal Lipovitellin-phosvitin complex, superhelical domain Vitellinogen, beta-sheet N-terminal Vitellinogen, open beta-sheet
UniProtKB:E7FBD3 4418
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations