Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-070702-4
Gene Name: apolipoprotein Ba
Gene Symbol: apoba
Previous Names: apob (1), im:6911942, wu:fb30e06, zmp:0000000614 (1)
Location: Chr: 17   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 4 publications
Directly Submitted Expression Data: 5 figures (4 images) from Thisse et al., 2004 [IMAGE:6911942]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  liver, unspecified, whole organism, YSL
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa11961, sa13626, sa13822
Knockdown reagents: MO1-apoba (1)
PHENOTYPE
Data: Fig. S3 from Avraham-Davidi et al., 2012
Observed in: sprouting angiogenesis, subintestinal vein

Phenotype of Human Orthologue OMIM Phenotype ID
Hypercholesterolemia, due to ligand-defective apo B 144010
Hypobetalipoproteinemia 615558
GENE ONTOLOGY
Ontology GO Term
Biological Process cholesterol transport (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function lipid transporter activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001747 (1)
  • InterPro:IPR009454 (1)
  • InterPro:IPR011030 (1)
  • InterPro:IPR015255 (1)
  • InterPro:IPR015816 (1)
  • InterPro:IPR015817 (1)
  • InterPro:IPR015818 (1)
  • InterPro:IPR015819 (1)
  • PROSITE:PS51211 (1)
  • Pfam:PF01347 (1)
  • Pfam:PF06448 (1)
  • Pfam:PF09172 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoba-001 (1) 13486
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM apoba No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    apoba Contained in: [BAC] CH211-117G17 (1) (order this)
    apoba Encodes: [EST] fb30e06, fc32g08, IMAGE:6911942 (1) (order this)
    apoba Has Artifact: [EST] fb79f11
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_689735 (1) 13480 bp
    Genomic GenBank:BX072551 (1) 164264 bp
    Select Tool
    Polypeptide UniProtKB:E7FBD3 (1) 4418 aa
    Sequence Clusters UniGene:51763 (1)
    Sequence Information (all 23)
    OTHER apoba GENE PAGES
  • Gene:566465 (1)
  • VEGA:OTTDARG00000038776 (1)
  • Ensembl(Zv9):ENSDARG00000042780 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish apoba 17  
    Human APOB 2 (2p24-p23)
  • OMIM:107730
  • Gene:338
  • Mouse Apob 12 ( 3.53 cM)
  • MGI:88052
  • Gene:238055
  • Orthology Details
    CITATIONS (21)