ZFIN ID: ZDB-GENE-070702-2
Gene Name: Werner syndrome
Gene Symbol: wrn
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including DNA binding activity, DNA helicase activity, and metal ion binding activity; predicted to be involved in several processes, including DNA geometric  ...
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH wrn HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Werner syndrome Werner syndrome 277700
DISEASE ASSOCIATED WITH wrn VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular metabolic process (more)
Cellular Component chromosome (more)
Molecular Function 3'-5' exonuclease activity (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001650 (1)
  • InterPro:IPR002121 (1)
  • InterPro:IPR002562 (1)
  • InterPro:IPR004589 (1)
  • InterPro:IPR010997 (1)
  • InterPro:IPR011545 (1)
  • InterPro:IPR012337 (1)
  • InterPro:IPR014001 (1)
  • InterPro:IPR018982 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR029491 (1)
  • InterPro:IPR032284 (1)
  • InterPro:IPR036388 (1)
  • InterPro:IPR036390 (1)
  • InterPro:IPR036397 (1)
  • PROSITE:PS50967 (1)
  • PROSITE:PS51192 (1)
  • PROSITE:PS51194 (1)
  • Pfam:PF00270 (1)
  • Pfam:PF00271 (1)
  • Pfam:PF00570 (1)
  • Pfam:PF01612 (1)
  • Pfam:PF09382 (1)
  • Pfam:PF14493 (1)
  • Pfam:PF16124 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wrn-202 (1) 4714
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM wrn No data available
    MARKER RELATIONSHIPS
    wrnContained in: [BAC] DKEYP-73E12
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009303971 (1)
    Genomic GenBank:BX537303 (1) 204522bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IHR6 (1) 1436aa
    Sequence Clusters UniGene:158499 (1)
    Sequence Information (all 10)
    OTHER wrn GENE PAGES
  • Alliance (1)
  • Gene:569495 (1)
  • VEGA:OTTDARG00000030845 (1)
  • Ensembl(GRCz11):ENSDARG00000098211 (1)
  • ORTHOLOGY for wrn (Chr: 10)
    CITATIONS (12)