Community Action Needed: Please respond to the NIH RFI
Gene

chmp2ba

ID
ZDB-GENE-070628-3
Name
charged multivesicular body protein 2Ba
Symbol
chmp2ba Nomenclature History
Previous Names
  • chmp2b
  • si:ch211-224m9.5
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to act upstream of or within vacuolar transport. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Is expressed in brain; opercular flap; retina; and trunk. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; chromosome 3-linked frontotemporal dementia; and frontotemporal dementia. Orthologous to human CHMP2B (charged multivesicular body protein 2B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Laboissonniere et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chmp2ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
chromosome 3-linked frontotemporal dementia Alliance Frontotemporal dementia and/or amyotrophic lateral sclerosis 7 600795
Associated With chmp2ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005024 Snf7 family
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations