ZFIN ID: ZDB-GENE-070621-1
Gene Name: six-cysteine containing astacin protease 1
Gene Symbol: c6ast1    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to the meprin A complex.
Genome Resources: Alliance (1),  Gene:751088 (1),  Ensembl(GRCz11):ENSDARG00000069216 (1)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH c6ast1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH c6ast1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Molecular Function hydrolase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001506 Peptidase M12A
Domain IPR006026 Peptidase, metallopeptidase
Domain IPR034039 Hatching enzyme, peptidase domain
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA c6ast1-201 (1)    Ensembl 1546
c6ast1-202 (1)    Ensembl 916
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM c6ast1 No data available
MARKER RELATIONSHIPS
c6ast1 Contained in: [BAC] DKEY-150L7 (order this)
c6ast1 Encodes: [cDNA] MGC:194228 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001043319 (1) 783 nt
Genomic GenBank:BX957297 (1) 79980 nt
Select Tool
Polypeptide UniProtKB:B3DHE9 (1) 275 aa
Sequence Information (all 12)
ORTHOLOGY for c6ast1 ( Chr: 7 )
CITATIONS (17)