ZFIN ID: ZDB-GENE-070619-1
Gene Name: diacylglycerol lipase, alpha
Gene Symbol: dagla    Nomenclature History

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Previous Name: nsddr (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits lipoprotein lipase activity. Involved in several processes, including endocannabinoid signaling pathway; optokinetic behavior; and swimming behavior. Predicted to localize to postsynaptic membrane. Is expressed in brain and cranial ganglion. Orthologous to human DAGLA (diacylglycerol lipase alpha).
Genome Resources: Alliance (1),  Gene:569398 (1),  Ensembl(GRCz11):ENSDARG00000062956 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9802 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34014 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dagla N/A 1
    MO2-dagla N/A 1
    DISEASE ASSOCIATED WITH dagla HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dagla VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function lipoprotein lipase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dagla-203 (1)    Ensembl 5848
    dagla-205 (1)    Ensembl 336
    ncRNA dagla-002 (1)    Ensembl 637
    dagla-003 (1)    Ensembl 846
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dagla No data available
    MARKER RELATIONSHIPS
    dagla Contained in: [BAC] CH73-119P20 (1), CH211-132L2 (1), CH211-236C4, RP71-3A8
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_692781 (1) 3024 nt
    Genomic GenBank:CT030046 (1) 174189 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q244 (1) 1076 aa
    Sequence Information (all 15)
    ORTHOLOGY for dagla ( Chr: 7 )
    CITATIONS (24)