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General Information
ZIRC
ZFIN ID: ZDB-GENE-070618-2
Gene Name: bone morphogenetic protein receptor, type II b (serine/threonine kinase)
Gene Symbol: bmpr2b
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits transforming growth factor beta-activated receptor activity. Involved in BMP signaling pathway; embryonic organ morphogenesis; and vasculature development. Predicted to localize to the  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026730Tg Transgenic Insertion Unknown Unknown DNA
la029534Tg Transgenic Insertion Unknown Unknown DNA
sa2507 Point Mutation Unknown Premature Stop ENU
sa5781 Point Mutation Unknown Premature Stop ENU
sa34578 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41374 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41375 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH bmpr2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    primary pulmonary hypertension Pulmonary hypertension, familial primary, 1, with or without HHT 178600
    Pulmonary hypertension, primary, fenfluramine or dexfenfluramine-associated 178600
    pulmonary venoocclusive disease Pulmonary venoocclusive disease 1 265450
    DISEASE ASSOCIATED WITH bmpr2b VIA EXPERIMENTAL MODELS No data available
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA bmpr2b-002 (1) 591
    mRNA bmpr2b-201 (1) 4030
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM bmpr2b No data available
    MARKER RELATIONSHIPS
    bmpr2bContained in: [BAC] DKEY-56K23 (1) (order this), DKEY-230P4 (1) (order this)
    bmpr2bEncodes: [cDNA] MGC:195171 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039807 (1) 4024bp
    Genomic GenBank:CR759883 (1) 213855bp Blast at MegaBLAST
    Polypeptide UniProtKB:B0V0H4 (1) 1071aa
    Sequence Clusters UniGene:134746 (1)
    Sequence Information (all 15)
    ORTHOLOGY for bmpr2b (Chr: 9)
    CITATIONS (36)