Gene

nrg2a

ID
ZDB-GENE-070615-10
Name
neuregulin 2a
Symbol
nrg2a Nomenclature History
Previous Names
  • nrg2
  • zgc:162973
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable signaling receptor binding activity. Acts upstream of or within several processes, including heart trabecula morphogenesis; neural crest cell migration; and skin epidermis development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in brain; epidermis; heart; median fin fold; and somite. Orthologous to human NRG2 (neuregulin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nrg2a Human Ortholog
No data available
Associated With nrg2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR002154 Neuregulin, C-terminal
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Family IPR040180 Neuregulin
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length EGF-like domain Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Neuregulin Neuregulin, C-terminal
UniProtKB:F1QKE1 565
UniProtKB:B9VQL3 565
UniProtKB:F1RCA4 492
UniProtKB:B9VQL2 494
UniProtKB:A5D6U9 488
UniProtKB:B9VQL1 492
UniProtKB:B9VQL4 289
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations