Gene
nrg2a
- ID
- ZDB-GENE-070615-10
- Name
- neuregulin 2a
- Symbol
- nrg2a Nomenclature History
- Previous Names
-
- nrg2
- zgc:162973
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable signaling receptor binding activity. Acts upstream of or within several processes, including heart trabecula morphogenesis; neural crest cell migration; and peripheral nervous system development. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in brain; epidermis; heart; median fin fold; and somite. Orthologous to human NRG2 (neuregulin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR002154 | Neuregulin, C-terminal |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Family | IPR040180 | Neuregulin |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | EGF-like domain | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype | Immunoglobulin subtype 2 | Neuregulin | Neuregulin, C-terminal |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5D6U9
|
488 | |||||||||
|
UniProtKB:F1RCA4
|
492 | |||||||||
|
UniProtKB:B9VQL1
|
492 | |||||||||
|
UniProtKB:F1QKE1
|
565 | |||||||||
|
UniProtKB:B9VQL4
|
289 | |||||||||
|
UniProtKB:B9VQL2
|
494 | |||||||||
|
UniProtKB:B9VQL3
|
565 |
Interactions and Pathways
No data available
Plasmids
No data available