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ZIRC
ZFIN ID: ZDB-GENE-070615-10
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Gene Name: neuregulin 2a
Gene Symbol: nrg2a
Sequence Ontology ID : SO:0001217

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Previous Names: nrg2, zgc:162973

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have signaling receptor binding activity. Involved in several processes, including heart trabecula morphogenesis; neural crest cell migration; and skin epidermis development. Predicted  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011165Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la021943Tg Transgenic Insertion Unknown Unknown DNA
    mn0237Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa23960 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 8 figures from 4 publications
    Observed in:
    DISEASE ASSOCIATED WITH nrg2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nrg2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neural crest cell migration (more)
    Cellular Component integral component of membrane (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR002154 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR036179 (1)
  • InterPro:IPR040180 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF02158 (1)
  • Pfam:PF07679 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nrg2a-201 (1) 2148
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrg2a
    MARKER RELATIONSHIPS
    nrg2a Contained in: [BAC] CH211-113H10 (1) (order this), DKEY-181C8 (1) (order this), DKEY-246I6 (1) (order this)
    nrg2a Encodes: [cDNA] MGC:162973 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001099254 (1) 2166 bp
    Select Tool
    Genomic GenBank:BX511240 (1) 175187 bp
    Select Tool
    Polypeptide UniProtKB:B9VQL3 (1) 565 aa
    Select Tool
    Sequence Clusters UniGene:77254 (1)
    Sequence Information (all 42)
    OTHER nrg2a GENE PAGES
  • Alliance (1)
  • Gene:100006951 (1)
  • VEGA:OTTDARG00000028365 (1)
  • Ensembl(GRCz11):ENSDARG00000077818 (2)
    • ORTHOLOGY for nrg2a ( Chr: 21 )
    CITATIONS (31)