ZFIN ID: ZDB-GENE-070604-1
Gene Name: Rho guanine nucleotide exchange factor (GEF) 11
Gene Symbol: arhgef11
Location: Chr: 7 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from Panizzi et al., 2007
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  central nervous system, head, pronephric duct, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa15205 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-arhgef11 (1), MO2-arhgef11 (1)
    PHENOTYPE
    Data: 7 figures from Panizzi et al., 2007
    Observed in: determination of left/right symmetry, heart, Kupffer's vesicle cilium, otolith organ (all 13) expand
    DISEASE ASSOCIATED WITH arhgef11 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process stress fiber assembly (more)
    Cellular Component cytoplasm (more)
    Molecular Function G-protein alpha-subunit binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR001331 (1)
  • InterPro:IPR001478 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR015212 (1)
  • InterPro:IPR016137 (1)
  • PROSITE:PS00741 (1)
  • PROSITE:PS50010 (1)
  • PROSITE:PS50106 (1)
  • Pfam:PF00595 (1)
  • Pfam:PF00621 (1)
  • Pfam:PF09128 (1)
  • Pfam:PF16652 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arhgef11-001 (1) 2252
    arhgef11-003 (1) 521
    ottdart00000063025 (1) 5755
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef11 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    arhgef11Contained in: [BAC] DKEYP-67A8 (1)
    arhgef11Encodes: [cDNA] MGC:195123 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001031840 (1) 4254bp
    Genomic RefSeq:NW_003334545 (1) 93268bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IRT3 (1) 1418aa
    Sequence Clusters UniGene:88842 (1)
    Sequence Information (all 20)
    OTHER arhgef11 GENE PAGES
  • Gene:565268 (1)
  • VEGA:OTTDARG00000023680 (1)
  • Ensembl(GRCz10):ENSDARG00000052482 (1)
  • ORTHOLOGY for arhgef11 (Chr: 7)
    Species Symbol Chromosome Accession # Evidence
    Human ARHGEF11 1
  • Gene:9826
  • OMIM:605708
  • HGNC:14580
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (16)