Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-070604-1
Gene Name: Rho guanine nucleotide exchange factor (GEF) 11
Gene Symbol: arhgef11
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from Panizzi et al., 2007
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  central nervous system, head, pronephric duct, whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: sa15205, vu7
Knockdown reagents: MO1-arhgef11 (1), MO2-arhgef11 (1)
PHENOTYPE
Data: 7 figures from Panizzi et al., 2007
Observed in: determination of left/right symmetry, heart, Kupffer's vesicle cilium, otolith organ (all 13) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process stress fiber assembly (more)
Cellular Component cytoplasm (more)
Molecular Function G-protein alpha-subunit binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR001331 (1)
  • InterPro:IPR001478 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR015212 (1)
  • InterPro:IPR015721 (1)
  • InterPro:IPR016137 (1)
  • PROSITE:PS00741 (1)
  • PROSITE:PS50010 (1)
  • PROSITE:PS50106 (1)
  • Pfam:PF00595 (1)
  • Pfam:PF00621 (1)
  • Pfam:PF09128 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arhgef11-001 (1) 2158
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef11 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    arhgef11 Contained in: [BAC] DKEYP-67A8 (1)
    arhgef11 Encodes: [cDNA] MGC:195123 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001031840 (1) 4254 bp
    Genomic RefSeq:NW_003334545 (1) 92104 bp Blast at MegaBLAST
    Polypeptide UniProtKB:B3DJQ2 (1) 1417 aa
    Sequence Clusters UniGene:88842 (1)
    Sequence Information (all 19)
    OTHER arhgef11 GENE PAGES
  • Gene:565268 (1)
  • VEGA:OTTDARG00000023680 (1)
  • Ensembl(Zv9):ENSDARG00000052482 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish arhgef11 7  
    Human ARHGEF11 1 (1q21)
  • OMIM:605708
  • Gene:9826
  • Orthology Details
    CITATIONS (17)