ZFIN ID: ZDB-GENE-070604-1
Gene Name: Rho guanine nucleotide exchange factor (GEF) 11
Gene Symbol: arhgef11
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from Panizzi et al., 2007
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
  central nervous system, head, pronephric duct, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa15205 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-arhgef11 (1), MO2-arhgef11 (1)
    PHENOTYPE
    Data: 7 figures from Panizzi et al., 2007
    Observed in: determination of left/right symmetry, heart, Kupffer's vesicle cilium, otolith organ (all 13) expand
    DISEASE ASSOCIATED WITH arhgef11 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process stress fiber assembly (more)
    Cellular Component cytoplasm (more)
    Molecular Function G-protein alpha-subunit binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR001331 (1)
  • InterPro:IPR001478 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR015212 (1)
  • InterPro:IPR015721 (1)
  • InterPro:IPR016137 (1)
  • PROSITE:PS00741 (1)
  • PROSITE:PS50010 (1)
  • PROSITE:PS50106 (1)
  • Pfam:PF00595 (1)
  • Pfam:PF00621 (1)
  • Pfam:PF09128 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arhgef11-001 (1) 2158
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef11 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    arhgef11 Contained in: [BAC] DKEYP-67A8 (1)
    arhgef11 Encodes: [cDNA] MGC:195123 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001031840 (1) 4254 bp
    Genomic RefSeq:NW_003334545 (1) 93268 bp Blast at MegaBLAST
    Polypeptide UniProtKB:B3DJQ2 (1) 1417 aa
    Sequence Clusters UniGene:88842 (1)
    Sequence Information (all 19)
    OTHER arhgef11 GENE PAGES
  • Gene:565268 (1)
  • VEGA:OTTDARG00000023680 (1)
  • Ensembl(Zv9):ENSDARG00000052482 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish arhgef11 7  
    Human ARHGEF11 1 (1q21)
  • OMIM:605708
  • Gene:9826
  • Orthology Details
    CITATIONS (17)