Gene
zfhx4
- ID
- ZDB-GENE-070530-3
- Name
- zinc finger homeobox 4
- Symbol
- zfhx4 Nomenclature History
- Previous Names
-
- im:7159242 (1)
- si:ch211-94d7.1
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in brain; midbrain neural keel; pharyngeal arch; and retinal ganglion cell layer. Orthologous to human ZFHX4 (zinc finger homeobox 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7159242 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital ptosis | Alliance | ?Ptosis, congenital | 178300 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeobox domain |
| Domain | IPR003604 | Matrin/U1-C-like, C2H2-type zinc finger |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Homologous_superfamily | IPR009057 | Homeobox-like domain superfamily |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
Domain Details Per Protein
| Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox-like domain superfamily | Matrin/U1-C-like, C2H2-type zinc finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F6NXU9
|
3528 | ||||||
|
UniProtKB:E7FCF7
|
3489 |
Interactions and Pathways
No data available
Plasmids
No data available