ZFIN ID: ZDB-GENE-070523-1
Gene Name: FERM domain containing 3
Gene Symbol: frmd3    Nomenclature History

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Previous Name: ferm3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have cytoskeletal protein binding activity. Predicted to be involved in actomyosin structure organization. Predicted to localize to the cytoskeleton and integral component of membrane. Orthologous to human FRMD3 (FERM domain containing 3).
Genome Resources: Alliance (1),  Gene:100331256 (1),  Ensembl(GRCz11):ENSDARG00000059885 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026626Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10479 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27276 Point Mutation Unknown Splice Site ENU
    sa34496 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH frmd3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH frmd3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actomyosin structure organization (more)
    Cellular Component cytoskeleton (more)
    Molecular Function cytoskeletal protein binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000299 FERM domain
    Family IPR000798 Ezrin/radixin/moesin-like
    Homologous_superfamily IPR011993 PH-like domain superfamily
    Homologous_superfamily IPR014352 FERM/acyl-CoA-binding protein superfamily
    Domain IPR014847 FERM adjacent (FA)
    Domain IPR018979 FERM, N-terminal
    Domain IPR018980 FERM, C-terminal PH-like domain
    Conserved_site IPR019747 FERM conserved site
    Domain IPR019748 FERM central domain
    Domain IPR019749 Band 4.1 domain
    Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
    Homologous_superfamily IPR035963 FERM superfamily, second domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA frmd3-202 (1)    Ensembl 411
    frmd3-203 (1)    Ensembl 1255
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM frmd3 No data available
    MARKER RELATIONSHIPS
    frmd3 Contained in: [BAC] CH73-230E15 (1), CH73-275J21 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002663231 (1) 2175 bp
    Genomic GenBank:CU467864 (1) 84113 bp
    Select Tool
    Polypeptide UniProtKB:B8JLE7 (1) 380 aa
    Sequence Information (all 15)
    ORTHOLOGY for frmd3 ( Chr: 8 )
    CITATIONS (20)