ZFIN ID: ZDB-GENE-070521-3
Gene Name: transcription factor B2, mitochondrial
Gene Symbol: tfb2m    Nomenclature History

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Previous Name: sb:cb857

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in mitochondrial transcription and rRNA methylation. Predicted to localize to the mitochondrial matrix. Is expressed in several structures, including alar plate midbrain region; immature eye; mesoderm; midbrain; and optic primordium. Orthologous to human TFB2M (transcription factor B2, mitochondrial).
Genome Resources: Alliance (1),  Gene:569468 (1),  Ensembl(GRCz11):ENSDARG00000074756 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2933 Point Mutation Unknown Premature Stop ENU
sa10078 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36345 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tfb2m HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tfb2m VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process methylation (more)
    Cellular Component mitochondrion (more)
    Molecular Function methyltransferase activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal
    Family IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm
    Family IPR016861 Mitochondrial transcription factor TFB2
    Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tfb2m-201 (1)    Ensembl 1894
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tfb2m No data available
    MARKER RELATIONSHIPS
    tfb2m Contained in: [BAC] DKEY-246M15 (order this)
    tfb2m Encodes: [EST] cb857 (1) (order this)
    [cDNA] MGC:174927 (1), MGC:198274 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001113617 (1) 1893 nt
    Genomic GenBank:BX470113 (1) 118640 nt
    Select Tool
    Polypeptide UniProtKB:A8WGQ8 (1) 437 aa
    Sequence Information (all 17)
    ORTHOLOGY for tfb2m ( Chr: 17 )
    CITATIONS (22)