ZFIN ID: ZDB-GENE-070510-3
Gene Name: phospholipase D1b
Gene Symbol: pld1b    Nomenclature History

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Previous Name: si:dkey-83f6.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have phospholipase D activity. Predicted to be involved in cell motility; phospholipid catabolic process; and regulation of microvillus assembly. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in developmental cardiac valvular defect. Orthologous to human PLD1 (phospholipase D1).
Genome Resources: Alliance (1),  Gene:572492 (1),  Ensembl(GRCz11):ENSDARG00000057125 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1311 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6775 Point Mutation Unknown Premature Stop ENU
    sa14680 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37906 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44158 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • DISEASE ASSOCIATED WITH pld1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    developmental cardiac valvular defect Alliance Cardiac valvular defect, developmental 212093
    DISEASE ASSOCIATED WITH pld1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inositol lipid-mediated signaling (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pld1b-201 (1)    Ensembl 4231
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pld1b No data available
    MARKER RELATIONSHIPS
    pld1b Contained in: [BAC] DKEY-83F6 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_021470348 (1)
    Genomic GenBank:CU406336 (1) 151564 nt
    Select Tool
    Polypeptide UniProtKB:F1QKJ2 (1) 1042 aa
    Sequence Information (all 11)
    ORTHOLOGY for pld1b ( Chr: 24 )
    CITATIONS (21)