Gene
ghrh
- ID
- ZDB-GENE-070426-1
- Name
- growth hormone releasing hormone
- Symbol
- ghrh Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Exhibits growth hormone-releasing hormone activity. Involved in signal transduction. Predicted to localize to extracellular space; perikaryon; and terminal bouton. Human ortholog(s) of this gene implicated in autoimmune polyendocrine syndrome type 1; endometrial cancer; ovarian cancer; and renal cell carcinoma. Orthologous to human GHRH (growth hormone releasing hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Gigantism due to GHRF hypersecretion | |||
| ?Isolated growth hormone deficiency due to defect in GHRF |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glucagon/GIP/secretin/VIP | VIP/GHRH-like |
|---|---|---|---|
|
UniProtKB:A0A181
|
112 |
Interactions and Pathways
No data available
Plasmids
No data available