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ZIRC
ZFIN ID: ZDB-GENE-070424-84
Gene Name: ATP-binding cassette, sub-family G (WHITE), member 1
Gene Symbol: abcg1    Nomenclature History

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Previous Name: zgc:162197

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have ATPase-coupled sterol transmembrane transporter activity; cholesterol transfer activity; and phospholipid transporter activity. Involved in regulation of cholesterol efflux and sprouting angiogenesis. Predicted to localize to the plasma membrane. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1).
Genome Resources: Alliance (1),  Gene:556979 (1),  Ensembl(GRCz11):ENSDARG00000063475 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22581 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35797 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35798 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35799 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-abcg1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abcg1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH abcg1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cholesterol efflux (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abcg1-201 (1)    Ensembl 3390
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcg1 No data available
    MARKER RELATIONSHIPS
    abcg1 Contained in: [BAC] CH211-83F7 (1) (order this), CH211-222M15 (1) (order this)
    abcg1 Encodes: [cDNA] MGC:162197 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110454 (1) 3278 bp
    Genomic GenBank:AL954822 (1) 219495 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A4QNW0 (1) 673 aa
    Sequence Clusters UniGene:118138 (1)
    Sequence Information (all 12)
    ORTHOLOGY for abcg1 ( Chr: 15 )
    CITATIONS (24)