ZFIN ID: ZDB-GENE-070424-82
Gene Name: RAS guanyl releasing protein 3 (calcium and DAG-regulated)
Gene Symbol: rasgrp3    Nomenclature History

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Previous Name: zgc:162151

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity; calcium ion binding activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction and regulation of GTPase activity. Is expressed in blood island; central nervous system; and trunk vasculature. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human RASGRP3 (RAS guanyl releasing protein 3).
Genome Resources: Alliance (1),  Gene:563441 (1),  Ensembl(GRCz11):ENSDARG00000077864 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027824Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28849 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rasgrp3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rasgrp3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rasgrp3-201 (1)    Ensembl 3394
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rasgrp3 No data available
    MARKER RELATIONSHIPS
    rasgrp3 Contained in: [BAC] CH211-195B21 (1)
    rasgrp3 Encodes: [cDNA] MGC:162151 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001110464 (1) 3396 nt
    Genomic GenBank:AL935174 (1) 195606 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QMH0 (1) 715 aa
    Sequence Information (all 15)
    ORTHOLOGY for rasgrp3 ( Chr: 17 )
    CITATIONS (22)