Gene

farp1

ID
ZDB-GENE-070424-163
Name
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Symbol
farp1 Nomenclature History
Previous Names
  • si:ch211-235f1.1
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have Rac guanyl-nucleotide exchange factor activity; phosphatidylinositol phosphate binding activity; and phosphatidylserine binding activity. Involved in glomerular filtration. Predicted to localize to cytoskeleton. Orthologous to human FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Rinschen et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With farp1 Human Ortholog
No data available
Associated With farp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019747 FERM conserved site
Domain IPR000219 Dbl homology (DH) domain
Domain IPR000299 FERM domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR014847 FERM adjacent (FA)
Domain IPR018979 FERM, N-terminal
Domain IPR018980 FERM, C-terminal PH-like domain
Domain IPR019748 FERM central domain
Domain IPR019749 Band 4.1 domain
Domain IPR041788 FARP1/FARP2/FRMD7, FERM domain C-lobe
Family IPR000798 Ezrin/radixin/moesin-like
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR014352 FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR035963 FERM superfamily, second domain
Domain Details Per Protein
Protein Length Band 4.1 domain Dbl homology (DH) domain Dbl homology (DH) domain superfamily Ezrin/radixin/moesin-like FARP1/FARP2/FRMD7, FERM domain C-lobe FERM/acyl-CoA-binding protein superfamily FERM adjacent (FA) FERM central domain FERM conserved site FERM, C-terminal PH-like domain FERM domain FERM, N-terminal FERM superfamily, second domain PH-like domain superfamily Pleckstrin homology domain Ubiquitin-like domain superfamily
UniProtKB:E9QIC8 1025
UniProtKB:B8JHS1 141
UniProtKB:A0A2R8QU98 262
UniProtKB:B8JHS0 811
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations