ZFIN ID: ZDB-GENE-070424-163
Gene Name: FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Gene Symbol: farp1    Nomenclature History

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Previous Name: si:ch211-235f1.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have Rac guanyl-nucleotide exchange factor activity; phosphatidylinositol phosphate binding activity; and phosphatidylserine binding activity. Involved in glomerular filtration. Predicted to localize to cytoskeleton. Orthologous to human FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1).
Genome Resources: Alliance (1),  Gene:100329707 (1),  Ensembl(GRCz11):ENSDARG00000074381 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028105Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9536 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25509 Point Mutation Unknown Premature Stop ENU
    sa38239 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39532 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko76b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-farp1 1
    MO1-farp1 N/A 1
    DISEASE ASSOCIATED WITH farp1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH farp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glomerular filtration (more)
    Cellular Component cytoskeleton (more)
    Molecular Function phosphatidylinositol binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA farp1-201 (1)    Ensembl 824
    farp1-203 (1)    Ensembl 3696
    farp1-204 (1)    Ensembl 2616
    ncRNA farp1-003 (1)    Ensembl 560
    farp1-005 (1) 638
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM farp1 No data available
    MARKER RELATIONSHIPS
    farp1 Contained in: [BAC] CH73-269M4 (1), CH211-235F1 (1)
    farp1 Has Artifact: [cDNA] MGC:112136 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_017355952 (1)
    Genomic GenBank:CR352215 (1) 156798 nt
    Select Tool
    Polypeptide UniProtKB:E9QIC8 (1) 1025 aa
    Sequence Information (all 22)
    ORTHOLOGY for farp1 ( Chr: 1 )
    CITATIONS (20)