ZFIN ID: ZDB-GENE-070424-110
Gene Name: NLR family pyrin domain containing 3
Gene Symbol: nlrp3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: si:ch211-114l13.10, si:dkey-156m2.3

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have ATP binding activity.
Genome Resources: Alliance (1),  Gene:567964 (1),  Ensembl(GRCz11):ENSDARG00000078620 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31246 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32798 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32799 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32801 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-nlrp3 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nlrp3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant nonsyndromic deafness 34 Alliance Deafness, autosomal dominant 34, with or without inflammation 617772
    CINCA Syndrome Alliance CINCA syndrome 607115
    familial cold autoinflammatory syndrome 1 Alliance Familial cold inflammatory syndrome 1 120100
    Muckle-Wells syndrome Alliance Muckle-Wells syndrome 191900
    Keratoendothelitis fugax hereditaria 148200
    DISEASE ASSOCIATED WITH nlrp3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA si:dkey-156m2.3-201 (1)    Ensembl 6595
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nlrp3 No data available
    MARKER RELATIONSHIPS
    nlrp3 Contained in: [BAC] CH211-114L13 (1), DKEY-156M2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_017355939 (1)
    Genomic GenBank:CU302202 (1) 202236 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A9JRG2 (1) 263 aa
    Sequence Information (all 8)
    ORTHOLOGY for nlrp3 ( Chr: 1 )
    CITATIONS (12)