Gene
slc9a6a
- ID
- ZDB-GENE-070424-104
- Name
- solute carrier family 9 member A6a
- Symbol
- slc9a6a Nomenclature History
- Previous Names
-
- fv47b07
- wu:fv47b07
- zgc:163055
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to act upstream of or within proton transmembrane transport; regulation of pH; and sodium ion transport. Predicted to be located in recycling endosome membrane. Predicted to be active in plasma membrane and recycling endosome. Human ortholog(s) of this gene implicated in Christianson syndrome. Orthologous to human SLC9A6 (solute carrier family 9 member A6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Christianson syndrome | Alliance | Intellectual developmental disorder, X-linked syndromic, Christianson type | 300243 |
| Neurodegenerative disorder, X-linked, female-restricted, with parkinsonism and cognitive impairement | 301142 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cation/H+ exchanger, CPA1 family | Na+/H+ exchanger | Sodium/hydrogen exchanger 6/7/9 |
|---|---|---|---|---|
|
UniProtKB:F1QSJ6
|
697 | |||
|
UniProtKB:A0A8M3AP93
|
732 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc9a6a-201
(1)
|
Ensembl | 8,162 nt | ||
| ncRNA |
slc9a6a-002
(1)
|
Ensembl | 666 nt |
Interactions and Pathways
No data available
Plasmids
No data available