ZFIN ID: ZDB-GENE-070424-1
Gene Name: kit ligand a
Gene Symbol: kitlga
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: kitla (1), slk (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 6 publications
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
  epiphysis, gut, integument, myotome (all 8) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24647 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa44268 Point Mutation Unknown Splice Site ENU
    tc244b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-kitlga (1)
    PHENOTYPE
    Data: 6 figures from 4 publications
    Observed in: apoptotic process, melanocyte, pigment cell, trunk neural crest cell (all 6) expand
    DISEASE ASSOCIATED WITH kitlga HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant nonsyndromic deafness 69 Deafness, autosomal dominant 69, unilateral or asymmetric 616697
    Hyperpigmentation with or without hypopigmentation 145250
    [Skin/hair/eye pigmentation 7, blond/brown hair] 611664
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process melanocyte differentiation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function stem cell factor receptor binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003452 (1)
  • InterPro:IPR009079 (1)
  • Pfam:PF02404 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA kitlga-001 (1) 1613
    kitlga-002 (1) 801
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM kitlga
    Tg(CMV:kitlga-JRed), Tg(hsp70l:kitlga), Tg(hsp70l:kitlga,csf1a,NLS-CFP), Tg(hsp70l:kitlga,csf1b,NLS-CFP)
    MARKER RELATIONSHIPS
    kitlgaContained in: [BAC] DKEY-30I6 (1) (order this), DKEY-106N21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001018123 (1) 819bp
    Genomic GenBank:BX901919 (1) 233401bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q56JH6 (1) 272aa
    Sequence Clusters UniGene:84231 (1)
    Sequence Information (all 12)
    OTHER kitlga GENE PAGES
  • Alliance (1)
  • Gene:553179 (1)
  • VEGA:OTTDARG00000028394 (1)
  • Ensembl(GRCz10):ENSDARG00000070917 (1)
  • ORTHOLOGY for kitlga (Chr: 25)
    CITATIONS (33)