Gene
kitlga
- ID
- ZDB-GENE-070424-1
- Name
- kit ligand a
- Symbol
- kitlga Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have cytokine activity and stem cell factor receptor binding activity. Involved in melanocyte differentiation. Predicted to localize to plasma membrane. Is expressed in several structures, including endocrine system; gut; integument; neural crest cell; and segmental plate. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 69 and familial progressive hyperpigmentation with or without hypopigmentation. Orthologous to human KITLG (KIT ligand).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Four-helical cytokine-like, core | Stem cell factor |
---|---|---|---|
UniProtKB:Q56JH6
|
272 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
kitlga-201
(1)
|
Havana | 1613 nt | |
mRNA |
kitlga-202
(1)
|
Havana | 801 nt | |
mRNA |
kitlga-203
(1)
|
Ensembl | 819 nt |
Interactions and Pathways
Plasmids