ZFIN ID: ZDB-GENE-070410-58
Gene Name: heat shock protein 70 family, member 13
Gene Symbol: hspa13    Nomenclature History

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Previous Name: zgc:162281

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in liver and post-vent region. Orthologous to human HSPA13 (heat shock protein family A (Hsp70) member 13).
Genome Resources: Alliance (1),  Gene:560481 (1),  Ensembl(GRCz11):ENSDARG00000040984 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Pei et al., 2018
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hg78 Small Deletion Unknown Unknown CRISPR
hg79 Small Deletion Unknown Unknown CRISPR
la012719Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15986 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16121 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28474 Point Mutation Unknown Premature Stop ENU
    sa35914 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hspa13 1
    PHENOTYPE
    Data: Fig. 2 from Pei et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH hspa13 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hspa13 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to unfolded protein (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hspa13-201 (1)    Ensembl 2001
    ncRNA hspa13-002 (1)    Ensembl 786
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hspa13 No data available
    MARKER RELATIONSHIPS
    hspa13 Contained in: [BAC] CH211-149M17 (1)
    hspa13 Encodes: [cDNA] MGC:162281 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001089479 (1) 1970 nt
    Genomic GenBank:BX324227 (1) 129726 nt
    Select Tool
    Polypeptide UniProtKB:A4QNX8 (1) 438 aa
    Sequence Information (all 9)
    ORTHOLOGY for hspa13 ( Chr: 15 )
    CITATIONS (21)