Gene
dnai2a
- ID
- ZDB-GENE-070410-46
- Name
- dynein, axonemal, intermediate chain 2a
- Symbol
- dnai2a Nomenclature History
- Previous Names
-
- zgc:162235
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to contribute to ATP-dependent microtubule motor activity, plus-end-directed. Predicted to be involved in cilium movement and outer dynein arm assembly. Predicted to localize to outer dynein arm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 9. Orthologous to human DNAI2 (dynein axonemal intermediate chain 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 9 | Alliance | Ciliary dyskinesia, primary, 9, with or without situs inversus | 612444 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IUW7
|
567 | ||||
|
UniProtKB:A7YYA2
|
555 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
dnai2a-202
(1)
|
Havana | 2307 nt |
Interactions and Pathways
No data available
Plasmids
No data available