ZFIN ID: ZDB-GENE-070410-32
Gene Name: adrenoceptor beta 2, surface b
Gene Symbol: adrb2b
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:162188

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have adrenergic receptor activity; involved in regulation of heart rate; predicted to localize to the integral component of plasma membrane; orthologous to human ADRB2 (adrenoceptor beta  ...
GENE EXPRESSION
All Expression Data: 10 figures from 5 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6680 Point Mutation Unknown Premature Stop ENU
sa37355 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH adrb2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    obesity {Obesity, susceptibility to} 601665
    Beta-2-adrenoreceptor agonist, reduced response to
    {Asthma, nocturnal, susceptibility to} 600807
    DISEASE ASSOCIATED WITH adrb2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of heart rate (more)
    Cellular Component integral component of membrane (more)
    Molecular Function adrenergic receptor activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000276 (1)
  • InterPro:IPR002233 (1)
  • InterPro:IPR017452 (1)
  • PROSITE:PS00237 (1)
  • PROSITE:PS50262 (1)
  • Pfam:PF00001 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA adrb2b-201 (1) 3764
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM adrb2b No data available
    MARKER RELATIONSHIPS
    adrb2bContained in: [BAC] DKEY-212J2 (1) (order this)
    adrb2bEncodes: [cDNA] MGC:162188 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089471 (1) 3728bp
    Genomic GenBank:CR762496 (1) 239780bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QNL3 (1) 409aa
    Sequence Clusters UniGene:134232 (1)
    Sequence Information (all 16)
    OTHER adrb2b GENE PAGES
  • Alliance (1)
  • Gene:100037315 (1)
  • VEGA:OTTDARG00000028373 (1)
  • ORTHOLOGY for adrb2b (Chr: 21)
    CITATIONS (28)