ZFIN ID: ZDB-GENE-070410-24
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Gene Name: sphingosine-1-phosphate lyase 1
Gene Symbol: sgpl1
Sequence Ontology ID : SO:0000704

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Previous Names: spl (1), zgc:162153

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have pyridoxal phosphate binding activity and sphinganine-1-phosphate aldolase activity; predicted to be involved in ameboidal-type cell migration and sphingolipid catabolic process;  ...
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (4 images) from Thisse et al., 2004 [IMAGE:7163588]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012328Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22308 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sgpl1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    nephrotic syndrome type 14 Nephrotic syndrome, type 14 617575
    DISEASE ASSOCIATED WITH sgpl1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carboxylic acid metabolic process (more)
    Molecular Function carboxy-lyase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002129 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
    		•
  • Pfam:PF00282 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA sgpl1-201 (1) 3460
    Select Tool
    sgpl1-202 (1) 917
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sgpl1 No data available
    MARKER RELATIONSHIPS
    sgpl1Contained in: [BAC] CH211-213F9 (order this)
    sgpl1Encodes: [EST] IMAGE:7163588 (1) (order this)
    [cDNA] MGC:162153 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089469 (1) 3490bp
    Select Tool
    Genomic GenBank:BX663512 (1) 95646bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q3N8 (1) 574aa
    Select Tool
    Sequence Clusters UniGene:29876 (1)
    Sequence Information (all 15)
    OTHER sgpl1 GENE PAGES
  • Alliance (1)
  • Gene:100037312 (1)
  • VEGA:OTTDARG00000027749 (1)
  • Ensembl(GRCz11):ENSDARG00000061375 (2)
    • ORTHOLOGY for sgpl1 (Chr: 13)
    CITATIONS (23)