Gene

micu1

ID
ZDB-GENE-070410-22
Name
mitochondrial calcium uptake 1
Symbol
micu1 Nomenclature History
Previous Names
  • zgc:162148 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Predicted to be involved in calcium import into the mitochondrion and positive regulation of mitochondrial calcium ion concentration. Predicted to localize to integral component of mitochondrial membrane; mitochondrial intermembrane space; and uniplex complex. Is expressed in female organism; heart; and heart tube. Human ortholog(s) of this gene implicated in myopathy with extrapyramidal signs. Orthologous to human MICU1 (mitochondrial calcium uptake 1).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Soman et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With micu1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
myopathy with extrapyramidal signs Alliance Myopathy with extrapyramidal signs 615673
Associated With micu1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Family IPR039800 Calcium uptake protein 1/2/3
Homologous_superfamily IPR011992 EF-hand domain pair
Domain Details Per Protein
Protein Length Calcium uptake protein 1/2/3 EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair
UniProtKB:E9QGA3 485
UniProtKB:A0A2R8Q9T2 493
UniProtKB:F1QD29 202
UniProtKB:K0A5Q0 485
UniProtKB:A4IG32 489
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations