ZFIN ID: ZDB-GENE-070410-120
Gene Name: malonyl-CoA decarboxylase
Gene Symbol: mlycd    Nomenclature History

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Previous Name: zgc:162977

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have malonyl-CoA decarboxylase activity. Predicted to be involved in acetyl-CoA biosynthetic process; malonyl-CoA catabolic process; and positive regulation of fatty acid oxidation. Predicted to localize to mitochondrial matrix and peroxisomal matrix. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MLYCD (malonyl-CoA decarboxylase).
Genome Resources: Alliance (1),  Gene:100037349 (1),  Ensembl(GRCz11):ENSDARG00000104732 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027908Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mlycd HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Malonyl-CoA decarboxylase deficiency 248360
    DISEASE ASSOCIATED WITH mlycd VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fatty acid biosynthetic process (more)
    Cellular Component mitochondrial matrix (more)
    Molecular Function malonyl-CoA decarboxylase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mlycd-201 (1)    Ensembl 1839
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mlycd No data available
    MARKER RELATIONSHIPS
    mlycd Contained in: [BAC] CH211-107M12 (1), CH211-262K24 (1)
    mlycd Encodes: [cDNA] MGC:162977 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001089503 (1) 1859 nt
    Genomic RefSeq:NW_018395014 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A3KP65 (1) 504 aa
    Sequence Information (all 15)
    ORTHOLOGY for mlycd ( Chr: 18 )
    CITATIONS (17)