ZFIN ID: ZDB-GENE-070402-2
Gene Name: amyotrophic lateral sclerosis 2a (juvenile)
Gene Symbol: als2a

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Previous Names: als2, si:dkey-33m14.1 (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3525 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026736Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10766 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17354 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34579 Point Mutation Unknown Premature Stop ENU
    sa34580 Point Mutation Unknown Splice Site ENU
    sa41377 Point Mutation Unknown Splice Site ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH als2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    amyotrophic lateral sclerosis type 2 Amyotrophic lateral sclerosis 2, juvenile 205100
    Primary lateral sclerosis, juvenile 606353
    Spastic paralysis, infantile onset ascending 607225
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component axon (more)
    Molecular Function Rab GTPase binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR000408 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR003123 (1)
  • InterPro:IPR003409 (1)
  • InterPro:IPR009091 (1)
  • InterPro:IPR011993 (1)
  • PROSITE:PS00626 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50010 (1)
  • PROSITE:PS50012 (1)
  • PROSITE:PS51205 (1)
  • Pfam:PF00415 (1)
  • Pfam:PF02204 (1)
  • Pfam:PF02493 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA als2a-001 (1) 2979
    als2a-002 (1) 1337
    als2a-003 (1) 377
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM als2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    als2aContained in: [BAC] DKEY-33M14 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_679972 (1) 6151bp
    Genomic GenBank:BX571704 (1) 219065bp Blast at MegaBLAST
    Polypeptide UniProtKB:I7L9G3 (1) 1590aa
    Sequence Clusters UniGene:102729 (1)
    Sequence Information (all 16)
    OTHER als2a GENE PAGES
  • Gene:557014 (1)
  • VEGA:OTTDARG00000025589 (1)
  • Ensembl(GRCz10):ENSDARG00000075111 (1)
  • ORTHOLOGY for als2a (Chr: 9)
    Species Symbol Chromosome Accession # Evidence
    Human ALS2 2
  • Gene:57679
  • OMIM:606352
  • HGNC:443
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (21)