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ZIRC
ZFIN ID: ZDB-GENE-070318-1
Gene Name: eomesodermin homolog b
Gene Symbol: eomesb    Nomenclature History

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Previous Names: eom-b (1), Eomes2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II activating transcription factor binding activity; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in CD8-positive, alpha-beta T cell differentiation involved in immune response; formation of primary germ layer; and regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin. Is expressed in leukocyte and lymphocyte. Orthologous to human EOMES (eomesodermin).
Genome Resources: Alliance (1),  Gene:799447 (1),  Ensembl(GRCz11):ENSDARG00000104243 (1)
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17035 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22969 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22970 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-eomesb
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eomesb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH eomesb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 15)
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eomesb No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001083575 (1) 2642 bp
    Genomic GenBank:FQ323161 (1) 88744 bp
    Select Tool
    Polypeptide UniProtKB:A1IJT6 (1) 534 aa
    Sequence Clusters UniGene:111570 (1)
    Sequence Information (all 8)
    ORTHOLOGY for eomesb ( Chr: 16 )
    CITATIONS (26)