Gene

eomesb

ID
ZDB-GENE-070318-1
Name
eomesodermin homolog b
Symbol
eomesb Nomenclature History
Previous Names
  • eom-b (1)
  • Eomes2 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II activating transcription factor binding activity; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in CD8-positive, alpha-beta T cell differentiation involved in immune response; embryonic morphogenesis; and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Is expressed in leukocyte and lymphocyte. Orthologous to human EOMES (eomesodermin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eomesb Human Ortholog
No data available
Associated With eomesb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018186 Transcription factor, T-box, conserved site
Domain IPR032385 T-box transcription factor-associated
Domain IPR046360 T-box transcription factor, DNA-binding domain
Family IPR001699 T-box transcription factor
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding domain superfamily
Homologous_superfamily IPR036960 T-box superfamily
Domain Details Per Protein
Protein Length p53-like transcription factor, DNA-binding domain superfamily T-box superfamily T-box transcription factor T-box transcription factor-associated T-box transcription factor, DNA-binding domain Transcription factor, T-box, conserved site
UniProtKB:A1IJT6 534
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations