ZFIN ID: ZDB-GENE-070314-2
Gene Name: retinoid X receptor, alpha a
Gene Symbol: rxraa    Nomenclature History

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Previous Names: NR2B1-B (1), RXRalpha-B (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have nuclear receptor activity and retinoic acid-responsive element binding activity. Predicted to be involved in several processes, including regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to localize to RNA polymerase II transcription regulator complex and nucleus. Is expressed in several structures, including nervous system; neural crest; optic vesicle; segmental plate; and tail bud. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha).
Genome Resources: Alliance (1),  Gene:555578 (1),  Ensembl(GRCz11):ENSDARG00000057737 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021840Tg Transgenic Insertion Unknown Unknown DNA
la021841Tg Transgenic Insertion Unknown Unknown DNA
la021842Tg Transgenic Insertion Unknown Unknown DNA
la028311Tg Transgenic Insertion Unknown Unknown DNA
la028312Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • xu0419Gt Transgenic Insertion Unknown Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    TALEN1-rxraa
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rxraa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rxraa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component host cell nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rxraa-201 (1)    Ensembl 1380
    rxraa-203 (1)    Ensembl 878
    ncRNA rxraa-003 (1) 658
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rxraa No data available
    MARKER RELATIONSHIPS
    rxraa Contained in: [BAC] CH211-242A9 (1), DKEY-275N23 (1) (order this)
    rxraa Encodes: [EST] dq017629 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001161551 (1) 1377 nt
    Genomic GenBank:BX001031 (1) 192207 nt
    Select Tool
    Polypeptide UniProtKB:F1Q4V9 (1) 458 aa
    Sequence Information (all 19)
    ORTHOLOGY for rxraa ( Chr: 21 )
    CITATIONS (44)