Gene

pdlim4

ID
ZDB-GENE-070308-5
Name
PDZ and LIM domain 4
Symbol
pdlim4 Nomenclature History
Previous Names
  • ril (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have actin binding activity and muscle alpha-actinin binding activity. Predicted to be involved in actin cytoskeleton organization; heart development; and muscle structure development. Predicted to localize to Z disc; actin cytoskeleton; and adherens junction. Is expressed in several structures, including axial vasculature; digestive system; nervous system; segmental plate; and solid lens vesicle. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human PDLIM4 (PDZ and LIM domain 4).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Te Velthuis et al., 2007
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pdlim4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
osteoporosis Alliance {Osteoporosis, susceptibility to} 166710
Associated With pdlim4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR001781 Zinc finger, LIM-type
Domain IPR031847 Domain of unknown function DUF4749
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF4749 PDZ domain PDZ superfamily Zinc finger, LIM-type
UniProtKB:Q0PWB9 349
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations