Gene

sorbs2b

ID

ZDB-GENE-070308-3

Name

sorbin and SH3 domain containing 2b

Symbol

sorbs2b Nomenclature History

Previous Names

si:ch211-51g4.4 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Acts upstream of or within actin filament organization. Predicted to be located in cytoplasm; focal adhesion; and membrane. Is expressed in heart. Orthologous to human SORBS2 (sorbin and SH3 domain containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Ding et al., 2020

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Ding et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sorbs2b Human Ortholog

No data available

Associated With sorbs2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001452	SH3 domain
Domain	IPR003127	SoHo domain
Family	IPR028506	Sorbin and SH3 domain-containing protein
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	SH3 domain	SH3-like domain superfamily	SoHo domain	Sorbin and SH3 domain-containing protein
UniProtKB:B8A438 InterPro
UniProtKB:B8A5F6 InterPro	1230
UniProtKB:A0A2R8PWS1 InterPro	689
UniProtKB:B8A436 InterPro	1252
UniProtKB:F1Q5K7 InterPro	1569
UniProtKB:A0A0R4IW85 InterPro	1438
UniProtKB:B8A437 InterPro	253
UniProtKB:B8A435 InterPro	115
UniProtKB:A0A2R8QN78 InterPro	1601
UniProtKB:A0A2R8QP02 InterPro	1301

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Length (nt)	Analysis
mRNA	sorbs2b-201 (1) Ensembl	7015 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs2b-202 (1) Ensembl	924 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs2b-203 (1) Ensembl	346 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs2b-204 (1) Ensembl	480 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sorbs2b-205 (1) Ensembl	5743 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations