ZFIN ID: ZDB-GENE-070301-5
Gene Name: atypical chemokine receptor 3a
Gene Symbol: ackr3a    Nomenclature History

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Previous Names: cxcr7a (1), drRDC1a (1), si:dkey-191g15.12, si:dkeyp-74a11.11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor activity; chemokine binding activity; and coreceptor activity. Involved in chemotaxis and posterior lateral line neuromast primordium migration. Predicted to localize to integral component of membrane. Is expressed in several structures, including midbrain hindbrain boundary neural rod; midbrain neural rod; midbrain neural tube; presumptive endoderm; and rhombomere. Orthologous to human ACKR3 (atypical chemokine receptor 3).
Genome Resources: Alliance (1),  Gene:100000764 (1),  Ensembl(GRCz11):ENSDARG00000062478 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34640 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ackr3a N/A 1
    MO2-ackr3a N/A 1
    DISEASE ASSOCIATED WITH ackr3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ackr3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chemotaxis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function chemokine binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ackr3a-201 (1)    Ensembl 2556
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ackr3a No data available
    MARKER RELATIONSHIPS
    ackr3a Contained in: [BAC] DKEYP-74A11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001144814 (1) 1583 nt
    Genomic GenBank:CR545476 (1) 202562 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1R6D3 (1) 398 aa
    Sequence Information (all 13)
    ORTHOLOGY for ackr3a ( Chr: 9 )
    CITATIONS (21)