Gene

brd2b

ID
ZDB-GENE-070220-1
Name
bromodomain containing 2b
Symbol
brd2b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Involved in thrombocyte differentiation. Human ortholog(s) of this gene implicated in B-cell lymphoma; B-lymphoblastic leukemia/lymphoma; juvenile myoclonic epilepsy; and photosensitivity disease. Is expressed in several structures, including head; immature eye; nervous system; ovary; and swim bladder. Orthologous to human BRD2 (bromodomain containing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Dibenedetto et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Bielczyk-MaczyƄska et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With brd2b Human Ortholog
No data available
Associated With brd2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018359 Bromodomain, conserved site
Domain IPR001487 Bromodomain
Domain IPR027353 NET domain
Domain IPR043508 Brdt, bromodomain, repeat I
Domain IPR043509 Brdt, bromodomain, repeat II
Homologous_superfamily IPR036427 Bromodomain-like superfamily
Homologous_superfamily IPR038336 NET domain superfamily
Domain Details Per Protein
Protein Length Brdt, bromodomain, repeat I Brdt, bromodomain, repeat II Bromodomain Bromodomain, conserved site Bromodomain-like superfamily NET domain NET domain superfamily
UniProtKB:F8W2E9 276
UniProtKB:F8W3C9 811
UniProtKB:Q7SXP6 558
UniProtKB:F1RBU8 409
UniProtKB:A8CYR7 276
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations