Gene
brd2b
- ID
- ZDB-GENE-070220-1
- Name
- bromodomain containing 2b
- Symbol
- brd2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Involved in thrombocyte differentiation. Human ortholog(s) of this gene implicated in B-cell lymphoma; B-lymphoblastic leukemia/lymphoma; juvenile myoclonic epilepsy; and photosensitivity disease. Is expressed in several structures, including head; immature eye; nervous system; ovary; and swim bladder. Orthologous to human BRD2 (bromodomain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Dibenedetto et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Bielczyk-Maczyńska et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018359 | Bromodomain, conserved site |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR027353 | NET domain |
| Domain | IPR043508 | Brdt, bromodomain, repeat I |
| Domain | IPR043509 | Brdt, bromodomain, repeat II |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
| Homologous_superfamily | IPR038336 | NET domain superfamily |
Domain Details Per Protein
| Protein | Length | Brdt, bromodomain, repeat I | Brdt, bromodomain, repeat II | Bromodomain | Bromodomain, conserved site | Bromodomain-like superfamily | NET domain | NET domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F8W2E9
|
276 | |||||||
|
UniProtKB:F8W3C9
|
811 | |||||||
|
UniProtKB:Q7SXP6
|
558 | |||||||
|
UniProtKB:F1RBU8
|
409 | |||||||
|
UniProtKB:A8CYR7
|
276 |
Interactions and Pathways
No data available
Plasmids
No data available