ZFIN ID: ZDB-GENE-070220-1
Gene Name: bromodomain containing 2b
Gene Symbol: brd2b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Involved in thrombocyte differentiation. Is expressed in several structures, including head; immature eye; nervous system; ovary; and swim bladder. Human ortholog(s) of this gene implicated in B-cell lymphoma; B-lymphoblastic leukemia/lymphoma; juvenile myoclonic epilepsy; and photosensitivity disease. Orthologous to human BRD2 (bromodomain containing 2).
Genome Resources: Alliance (1),  Gene:569354 (1),  Ensembl(GRCz11):ENSDARG00000046087 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14579 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-brd2b N/A 1
    MO2-brd2b N/A 1
    PHENOTYPE
    Data: Fig. S22 from Bielczyk-MaczyƄska et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH brd2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH brd2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process thrombocyte differentiation (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA brd2b-202 (1)    Ensembl 4037
    brd2b-203 (1)    Ensembl 1447
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM brd2b No data available
    MARKER RELATIONSHIPS
    brd2b Contained in: [BAC] CH73-31D8 (1), CH73-376G11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001110524 (1) 1467 nt
    Genomic GenBank:CU694227 (1) 121472 nt
    Select Tool
    Polypeptide UniProtKB:F8W3C9 (1) 811 aa
    Sequence Information (all 18)
    ORTHOLOGY for brd2b ( Chr: 16 )
    CITATIONS (18)