ZFIN ID: ZDB-GENE-070209-80
Gene Name: T-box 3a
Gene Symbol: tbx3a
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: tbx-b, tbx3, tbx3b, tbxb, zgc:158110 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA binding activity and DNA-binding activity transcription factor activity; involved in embryonic heart tube development; predicted to localize to the nucleus; orthologous to human  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1334 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16346 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18035 Point Mutation Unknown Missense, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26643 Point Mutation Unknown Missense, Premature Stop ENU
    sa40617 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Ribeiro et al., 2007
    Observed in:
    DISEASE ASSOCIATED WITH tbx3a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ulnar-mammary syndrome Ulnar-mammary syndrome 181450
    DISEASE ASSOCIATED WITH tbx3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic heart tube development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001699 (1)
  • InterPro:IPR002070 (1)
  • InterPro:IPR008967 (1)
  • InterPro:IPR018186 (1)
  • InterPro:IPR022582 (1)
  • InterPro:IPR036960 (1)
  • PROSITE:PS01264 (1)
  • PROSITE:PS01283 (1)
  • PROSITE:PS50252 (1)
  • Pfam:PF00907 (1)
  • Pfam:PF12598 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tbx3a-001 (1) 3872
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tbx3a No data available
    MARKER RELATIONSHIPS
    tbx3aContained in: [BAC] CH211-245E21 (1) (order this)
    tbx3aEncodes: [cDNA] MGC:158110 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001101670 (1) 3947bp
    Genomic GenBank:CU181811 (1) 144158bp
    Select Tool
    Polypeptide UniProtKB:A2RUW2 (1) 689aa
    Sequence Clusters UniGene:88318 (1)
    Sequence Information (all 13)
    OTHER tbx3a GENE PAGES
  • Alliance (1)
  • Gene:556870 (1)
  • VEGA:OTTDARG00000029273 (1)
  • Ensembl(GRCz11):ENSDARG00000002216 (2)
  • ORTHOLOGY for tbx3a (Chr: 5)
    CITATIONS (30)