Gene

rps6ka3b

ID
ZDB-GENE-070209-74
Name
ribosomal protein S6 kinase, polypeptide 3b
Symbol
rps6ka3b Nomenclature History
Previous Names
  • zgc:158386
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have ribosomal protein S6 kinase activity. Involved in ossification. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Coffin-Lowry syndrome; intellectual disability; and non-syndromic X-linked intellectual disability. Orthologous to human RPS6KA3 (ribosomal protein S6 kinase A3).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rps6ka3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Coffin-Lowry syndrome Alliance Coffin-Lowry syndrome 303600
non-syndromic X-linked intellectual disability Alliance Mental retardation, X-linked 19 300844
Associated With rps6ka3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR017892 Protein kinase, C-terminal
Domain IPR041906 Ribosomal S6 kinase, N-terminal catalytic domain
Family IPR016239 Ribosomal protein S6 kinase II
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal Protein kinase, ATP binding site Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Ribosomal protein S6 kinase II Ribosomal S6 kinase, N-terminal catalytic domain Serine/threonine-protein kinase, active site
UniProtKB:E9QIU5 692
UniProtKB:E7F469 722
UniProtKB:F1R2A7 709
UniProtKB:A0A2R8QG28 674
UniProtKB:A0A2R8QC98 689
UniProtKB:A2RUY2 720
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations