ZFIN ID: ZDB-GENE-070209-68
Gene Name: testis associated actin remodelling kinase 2
Gene Symbol: tesk2    Nomenclature History

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Previous Name: zgc:158349

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization. Predicted to localize to the cytoplasm and nucleus. Orthologous to human TESK2 (testis associated actin remodelling kinase 2).
Genome Resources: Alliance (1),  Gene:568213 (1),  Ensembl(GRCz11):ENSDARG00000061450 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2050 Point Mutation Unknown Premature Stop ENU
sa16291 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16358 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tesk2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tesk2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000719 Protein kinase domain
    Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
    Active_site IPR008266 Tyrosine-protein kinase, active site
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    Binding_site IPR017441 Protein kinase, ATP binding site
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tesk2-201 (1)    Ensembl 2541
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tesk2 No data available
    MARKER RELATIONSHIPS
    tesk2 Contained in: [BAC] DKEY-40I22 (1) (order this)
    tesk2 Encodes: [cDNA] MGC:158349 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110476 (1) 2540 bp
    Genomic GenBank:BX649522 (1) 155396 bp
    Select Tool
    Polypeptide UniProtKB:A2VCY1 (1) 634 aa
    Sequence Information (all 11)
    ORTHOLOGY for tesk2 ( Chr: 2 )
    CITATIONS (16)