ZFIN ID: ZDB-GENE-070209-188
Gene Name: SH2B adaptor protein 1
Gene Symbol: sh2b1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:158474

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in intracellular signal transduction. Predicted to localize to the plasma membrane. Orthologous to human SH2B1 (SH2B adaptor protein 1).
Genome Resources: Alliance (1),  Gene:558152 (1),  Ensembl(GRCz11):ENSDARG00000057679 (1)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sh2b1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH sh2b1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process signal transduction (more)
Cellular Component plasma membrane (more)
Molecular Function signaling adaptor activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001849 Pleckstrin homology domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain IPR015012 Phenylalanine zipper
Family IPR030521 SH2B adapter protein 1
Family IPR030523 SH2B adapter protein
Domain IPR035057 SH2B1, SH2 domain
Homologous_superfamily IPR036290 Phenylalanine zipper superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sh2b1-202 (1)    Ensembl 4210
sh2b1-203 (1)    Ensembl 882
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sh2b1 No data available
MARKER RELATIONSHIPS
sh2b1 Contained in: [BAC] CH211-66P13 (1)
sh2b1 Encodes: [cDNA] MGC:158474 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001110455 (1) 3618 bp
Genomic GenBank:BX784026 (1) 162371 bp
Select Tool
Polypeptide UniProtKB:A2RUZ0 (1) 906 aa
Sequence Information (all 15)
ORTHOLOGY for sh2b1 ( Chr: 3 )
CITATIONS (19)