ZFIN is now using GRCz12tu for Genomic Data
Gene
sh2b1
- ID
- ZDB-GENE-070209-188
- Name
- SH2B adaptor protein 1
- Symbol
- sh2b1 Nomenclature History
- Previous Names
-
- zgc:158474
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be active in plasma membrane. Orthologous to human SH2B1 (SH2B adaptor protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR015012 | Phenylalanine zipper |
| Domain | IPR035057 | SH2B1, SH2 domain |
| Family | IPR030523 | SH2B adapter protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036290 | Phenylalanine zipper superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Phenylalanine zipper | Phenylalanine zipper superfamily | PH-like domain superfamily | Pleckstrin homology domain | SH2B1, SH2 domain | SH2B adapter protein | SH2 domain | SH2 domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A2RUZ0 | InterPro | 906 | ||||||||
| UniProtKB:A0A8M2BAY6 | InterPro | 858 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers