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ZIRC
ZFIN ID: ZDB-GENE-070209-164
Gene Name: FOS like 2, AP-1 transcription factor subunit
Gene Symbol: fosl2    Nomenclature History

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Previous Names: wu:fl03b09, wu:fl17h04, xx:fl17h04, zgc:158347

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in regulation of cardiac muscle cell myoblast differentiation. Predicted to localize to the nucleus. Is expressed in head; presumptive bulbus arteriosus; presumptive cardiac ventricle heart tube; and trunk. Orthologous to human FOSL2 (FOS like 2, AP-1 transcription factor subunit).
Genome Resources: Alliance (1),  Gene:558921 (1),  Ensembl(GRCz11):ENSDARG00000040623 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fb15 Small Deletion Unknown Unknown TALEN
fb16 Small Deletion Unknown Frameshift, Premature Stop TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-fosl2 N/A 1
TALEN1-fosl2 1
DISEASE ASSOCIATED WITH fosl2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH fosl2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of cardiac muscle cell myoblast differentiation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 8)
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fosl2 No data available
MARKER RELATIONSHIPS
fosl2 Encodes: [EST] fl03b09 (1), fl17h04
[cDNA] MGC:158347 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001082998 (1)
Genomic GenBank:CABZ01079146 (1) 21472 bp
Polypeptide UniProtKB:A2RUX8 (1) 341 aa
Sequence Clusters UniGene:10410 (1)
Sequence Information (all 24)
ORTHOLOGY for fosl2 ( Chr: 17 )
CITATIONS (21)