ZFIN ID: ZDB-GENE-070206-9
Gene Name: neurexin 3a
Gene Symbol: nrxn3a    Nomenclature History

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Previous Names: nrxn3aa, nrxn3ab, im:7144250, wu:fj54c11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Predicted to be involved in angiogenesis and cell adhesion. Predicted to localize to integral component of membrane. Orthologous to human NRXN3 (neurexin 3).
Genome Resources: Alliance (1),  Gene:563598 (1),  Ensembl(GRCz11):ENSDARG00000043746 (2)
Note: nrxn3a has two isoforms, alpha (2 forms DQ641432 and DQ641433) and beta (DQ641434)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7144250]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019947Tg Transgenic Insertion Unknown Unknown DNA
la019948Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019949Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019950Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027815Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2921 Point Mutation Unknown Premature Stop ENU
    sa9245 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11330 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14031 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18056 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23034 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32142 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36371 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36372 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36373 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nrxn3a
    2
    CRISPR2-nrxn3a
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nrxn3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nrxn3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript nrxn3a-204 (1)    Ensembl 2987
    mRNA nrxn3a-203 (1)    Ensembl 2408
    nrxn3a-208 (1)    Ensembl 4008
    ncRNA nrxn3a-004 (1)    Ensembl 788
    nrxn3a-005 (1)    Ensembl 776
    nrxn3a-006 (1)    Ensembl 437
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrxn3a No data available
    MARKER RELATIONSHIPS
    nrxn3a Contained in: [BAC] CH211-154E6 (1), DKEY-109B24 (1) (order this), DKEY-153P6 (1) (order this), DKEY-245F17 (1) (order this), DKEYP-51D5 (1)
    nrxn3a Encodes: [EST] fj54c11, IMAGE:7144250 (1)
    [cDNA] MGC:174586 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001080009 (1) 7351 nt
    Genomic GenBank:BX571723 (1) 201159 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A1XQX8 (1) 1697 aa
    Sequence Information (all 66)
    ORTHOLOGY for nrxn3a ( Chr: 17 )
    CITATIONS (30)