ZFIN ID: ZDB-GENE-070206-5
Gene Name: neurexin 2a
Gene Symbol: nrxn2a    Nomenclature History

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Previous Names: nrxn2aa, nrxn2ab

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Involved in chemical synaptic transmission and motor neuron axon guidance. Predicted to localize to integral component of membrane. Is expressed in nervous system and spinal cord neural tube. Orthologous to human NRXN2 (neurexin 2).
Genome Resources: Alliance (1),  Gene:558326 (1),  Ensembl(GRCz11):ENSDARG00000061454 (2)
Note: nrxn2a has two isoforms, alpha (DQ641428) and beta (DQ641429)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010201Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014047Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la021939Tg Transgenic Insertion Unknown Unknown DNA
    la021940Tg Transgenic Insertion Unknown Unknown DNA
    la028338Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028340Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • mn0435Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16817 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18390 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32351 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45740 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nrxn2a
    2
    CRISPR2-nrxn2a
    2
    MO1-nrxn2a N/A 1
    MO2-nrxn2a N/A 1
    MO3-nrxn2a N/A 1
    MO4-nrxn2a N/A 1
    DISEASE ASSOCIATED WITH nrxn2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nrxn2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chemical synaptic transmission (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nrxn2a-201 (1)    Ensembl 4333
    nrxn2a-203 (1)    Ensembl 6930
    ncRNA nrxn2a-003 (1)    Ensembl 576
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrxn2a No data available
    MARKER RELATIONSHIPS
    nrxn2a Contained in: [BAC] CH73-93G12 (1), CH211-69J13 (1), CH211-101J8 (1), CH211-196O14 (1), CH211-247J24 (1), CH211-268G14 (1), CH211-268L18 (1), DKEY-28P18 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001079970 (1) 6930 nt
    Genomic GenBank:AL845282 (1) 192865 nt
    Select Tool
    Polypeptide UniProtKB:A1XQX4 (1) 1670 aa
    Sequence Information (all 60)
    ORTHOLOGY for nrxn2a ( Chr: 21 )
    CITATIONS (30)