Gene

nrxn1b

ID
ZDB-GENE-070206-3
Name
neurexin 1b
Symbol
nrxn1b Nomenclature History
Previous Names
  • nrxn1ba
  • nrxn1bb
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable metal ion binding activity. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Pitt-Hopkins-like syndrome 2. Orthologous to human NRXN1 (neurexin 1).
Genome Resources
Note
nrxn1b has two isoforms, alpha (DQ641426) and beta (DQ641427).
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nrxn1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Pitt-Hopkins-like syndrome 2 Alliance Pitt-Hopkins-like syndrome 2 614325
{Schizophrenia, susceptibility to, 17} 614332
Associated With nrxn1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR001791 Laminin G domain
Domain IPR003585 Neurexin/syndecan/glycophorin C
Domain IPR027789 Syndecan/Neurexin domain
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily EGF-like domain Laminin G domain Neurexin/syndecan/glycophorin C Syndecan/Neurexin domain
UniProtKB:A1XQX2 1470
UniProtKB:F1R7M4 448
UniProtKB:A0A2R8QPE8 448
UniProtKB:A0A2R8QEX7 1470
UniProtKB:A1XQX3 448
UniProtKB:F8W597 1475
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations