Gene
nrxn1b
- ID
- ZDB-GENE-070206-3
- Name
- neurexin 1b
- Symbol
- nrxn1b Nomenclature History
- Previous Names
-
- nrxn1ba
- nrxn1bb
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Predicted to be involved in cell adhesion. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Pitt-Hopkins-like syndrome 2. Orthologous to human NRXN1 (neurexin 1).
- Genome Resources
- Note
-
nrxn1b has two isoforms, alpha (DQ641426) and beta (DQ641427).
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Pitt-Hopkins-like syndrome 2 | Alliance | Pitt-Hopkins-like syndrome 2 | 614325 |
| {Schizophrenia, susceptibility to, 17} | 614332 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like domain | Laminin G domain | Neurexin/syndecan/glycophorin C | Syndecan/Neurexin domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B4Y5
|
1440 | |||||
|
UniProtKB:A1XQX3
|
448 | |||||
|
UniProtKB:F1R7M4
|
448 | |||||
|
UniProtKB:A0A8M3AYS8
|
1431 | |||||
|
UniProtKB:A1XQX2
|
1470 | |||||
|
UniProtKB:F8W597
|
1475 | |||||
|
UniProtKB:A0A8M9PXV2
|
217 | |||||
|
UniProtKB:A0A8M3B7R4
|
1457 | |||||
|
UniProtKB:A0A8M3AYQ8
|
1466 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
nrxn1b-201
(1)
|
Havana | 7191 nt | |
| mRNA |
nrxn1b-202
(1)
|
Havana | 6818 nt |
Interactions and Pathways
No data available
Plasmids
No data available