ZFIN ID: ZDB-GENE-070122-3
Gene Name: cadherin, EGF LAG seven-pass G-type receptor 3
Gene Symbol: celsr3    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor activity and calcium ion binding activity. Involved in gamma-aminobutyric acid signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in brain; eye; and muscle. Orthologous to human CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3).
Genome Resources: Alliance (1),  Gene:100008568 (1),  Ensembl(GRCz11):ENSDARG00000055825 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
celsr3_unrecovered Point Mutation Unknown Unknown ENU
fh339 Point Mutation Unknown Unknown ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2445 Point Mutation Unknown Premature Stop ENU
    sa7333 Point Mutation Unknown Splice Site ENU
    sa9305 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10576 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11108 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21306 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34415 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34416 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34417 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38693 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38694 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • w65 Point Mutation Exon 1 Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-celsr3 N/A 1
    MO2-celsr3 N/A 1
    DISEASE ASSOCIATED WITH celsr3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH celsr3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process gamma-aminobutyric acid signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA celsr3-202 (1)    Ensembl 1323
    celsr3-203 (1)    Ensembl 1219
    celsr3-204 (1)    Ensembl 6195
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM celsr3 No data available
    MARKER RELATIONSHIPS
    celsr3 Contained in: [BAC] CH211-122M4 (1), DKEY-20D21 (1) (order this), DKEY-90L2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009304014 (1)
    Genomic GenBank:CR847503 (1) 217514 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A9C3S7 (1) 2065 aa
    Sequence Information (all 20)
    ORTHOLOGY for celsr3 ( Chr: 8 )
    CITATIONS (26)