Gene
celsr3
- ID
- ZDB-GENE-070122-3
- Name
- cadherin, EGF LAG seven-pass G-type receptor 3
- Symbol
- celsr3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled receptor activity and calcium ion binding activity. Involved in gamma-aminobutyric acid signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in brain; eye; and muscle. Orthologous to human CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Lewis et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020894 | Cadherin conserved site |
| Domain | IPR000203 | GPS motif |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR002049 | Laminin-type EGF domain |
| Domain | IPR002126 | Cadherin-like |
| Domain | IPR017981 | GPCR, family 2-like |
| Domain | IPR032471 | GAIN domain, N-terminal |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR015919 | Cadherin-like superfamily |
| Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
Domain Details Per Protein
| Protein | Length | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like calcium-binding domain | EGF-like domain | GAIN domain, N-terminal | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2-like | GPCR, family 2, secretin-like | GPS motif | Laminin G domain | Laminin-type EGF domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R8J2
|
2014 | ||||||||||||||
|
UniProtKB:F1R6D5
|
441 | ||||||||||||||
|
UniProtKB:A9C3S7
|
2065 | ||||||||||||||
|
UniProtKB:F1R379
|
407 | ||||||||||||||
|
UniProtKB:A0JBX2
|
224 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
celsr3-202
(1)
|
1323 nt | |
| mRNA |
celsr3-203
(1)
|
1219 nt | |
| mRNA |
celsr3-204
(1)
|
6195 nt |
Interactions and Pathways
No data available
Plasmids
No data available