ZFIN ID: ZDB-GENE-070117-37
Gene Name: reversion-inducing-cysteine-rich protein with kazal motifs
Gene Symbol: reck    Nomenclature History

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Previous Names: nft (1), no food for thought (1), sdp, si:ch1073-416f3.1, zmp:0000000982

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have coreceptor activity involved in canonical Wnt signaling pathway and metalloendopeptidase inhibitor activity. Involved in several processes, including dorsal root ganglion development; regulation of cell migration involved in sprouting angiogenesis; and sprouting angiogenesis. Localizes to the plasma membrane. Is expressed in trunk and vasculature. Orthologous to human RECK (reversion inducing cysteine rich protein with kazal motifs).
Genome Resources: Alliance (1),  Gene:100334698 (1),  Ensembl(GRCz11):ENSDARG00000090039 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Pharyngula:Prim-15 (30.0h-36.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13352 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • w12 Point Mutation Exon 9 - Intron 9 Splice Junction Splice Site ENU
    w13 Point Mutation Exon 2 Missense ENU
    w14 Point Mutation Exon 9 Premature Stop ENU
    y72 Point Mutation Unknown Missense ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-reck N/A 2
    DISEASE ASSOCIATED WITH reck HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH reck VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal root ganglion development (more)
    Cellular Component plasma membrane (more)
    Molecular Function coreceptor activity involved in canonical Wnt signaling pathway (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR002350 Kazal domain
    Homologous_superfamily IPR036058 Kazal domain superfamily
    Family IPR039016 Reversion-inducing cysteine-rich protein with Kazal motifs
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA reck-003 (1) 645
    reck-201 (1)    Ensembl 4287
    ncRNA reck-002 (1) 590
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM reck No data available
    MARKER RELATIONSHIPS
    reck Contained in: [Fosmid] CH1073-59L16 (1), CH1073-416F3 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009297202 (1)
    Genomic GenBank:FP565452 (1) 38930 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IKU3 (1) 955 aa
    Sequence Information (all 13)
    ORTHOLOGY for reck ( Chr: 24 )
    CITATIONS (25)