ZFIN ID: ZDB-GENE-070117-2062
Gene Name: ectodysplasin A receptor
Gene Symbol: edar
Sequence Ontology ID : SO:0000704

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Previous Names: finless (1), fls (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have signaling receptor activity; involved in dermal bone morphogenesis and fin development; predicted to localize to the plasma membrane; orthologous to human EDAR (ectodysplasin A  ...
GENE EXPRESSION
All Expression Data: 6 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Days 21-29 (21d-30d, 7.8mm, 10 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dmh3 Point Mutation Unknown Missense ENU
dt1248 Point Mutation Unknown Unknown ENU
t0621 Point Mutation Unknown Unknown ENU
te370f Unknown Unknown Unknown ENU
PHENOTYPE
Data: 11 figures from 5 publications
Observed in:
DISEASE ASSOCIATED WITH edar HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
hypohidrotic ectodermal dysplasia Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant 129490
Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type, autosomal recessive 224900
[Hair morphology 1, hair thickness] 612630
DISEASE ASSOCIATED WITH edar VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process bone development (more)
Cellular Component integral component of membrane (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011029 (1)
  • InterPro:IPR034052 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM edar No data available
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001115064 (1)
    Genomic GenBank:CABZ01032671 (1) 38782bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IGE7 (1) 460aa
    Sequence Clusters UniGene:139207 (1)
    Sequence Information (all 13)
    OTHER edar GENE PAGES
  • Alliance (1)
  • Gene:796370 (1)
  • Ensembl(GRCz11):ENSDARG00000099088 (1)
  • ORTHOLOGY for edar (Chr: 9)
    CITATIONS (26)