Gene

dtna

ID
ZDB-GENE-070117-2
Name
dystrobrevin, alpha
Symbol
dtna Nomenclature History
Previous Names
  • atnb
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have zinc ion binding activity. Predicted to be involved in synaptic signaling. Predicted to localize to plasma membrane and synapse. Is expressed in brain; notochord; and somite. Human ortholog(s) of this gene implicated in cardiomyopathy and left ventricular noncompaction. Orthologous to human DTNA (dystrobrevin alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Böhm et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dtna Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
left ventricular noncompaction Alliance Left ventricular noncompaction 1, with or without congenital heart defects 604169
Myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis 2 620971
Associated With dtna Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000433 Zinc finger, ZZ-type
Domain IPR015153 EF-hand domain, type 1
Domain IPR015154 EF-hand domain, type 2
Family IPR017432 Distrobrevin
Family IPR050774 KCMF1 and Dystrophin
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR043145 Zinc finger, ZZ-type superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dtna-201 (1) Ensembl 2,342 nt
mRNA dtna-202 (1) Ensembl 2,415 nt
mRNA dtna-203 (1) Ensembl 2,145 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations