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Gene

gsk3aa

ID
ZDB-GENE-060503-796
Name
glycogen synthase kinase 3 alpha a
Symbol
gsk3aa Nomenclature History
Previous Names
  • sb:eu851
  • si:ch211-39e15.2
  • zgc:158379
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cell surface receptor signaling pathway; negative regulation of signal transduction; and regulation of neuron projection development. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in axon; cytosol; and nucleus. Is expressed in testis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gsk3aa Human Ortholog
No data available
Associated With gsk3aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR039192 Glycogen synthase kinase 3, catalytic domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Glycogen synthase kinase 3, catalytic domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:I3ISV4 244
UniProtKB:A1L1U4 359
UniProtKB:Q1LYN4 462
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations