ZFIN ID: ZDB-GENE-070112-622
Gene Name: phosphodiesterase 8A
Gene Symbol: pde8a    Nomenclature History

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Previous Name: zgc:158458

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have 3',5'-cyclic-nucleotide phosphodiesterase activity and metal ion binding activity. Predicted to be involved in phosphorelay signal transduction system and regulation of transcription, DNA-templated. Orthologous to human PDE8A (phosphodiesterase 8A).
Genome Resources: Alliance (1),  Gene:791145 (1),  Ensembl(GRCz11):ENSDARG00000087941 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa39507 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pde8a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pde8a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorelay signal transduction system (more)
    Molecular Function 3',5'-cyclic-nucleotide phosphodiesterase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000014 PAS domain
    Domain IPR001789 Signal transduction response regulator, receiver domain
    Domain IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
    Domain IPR003607 HD/PDEase domain
    Homologous_superfamily IPR011006 CheY-like superfamily
    Domain IPR013767 PAS fold
    Family IPR023088 3'5'-cyclic nucleotide phosphodiesterase
    Conserved_site IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved site
    Homologous_superfamily IPR035965 PAS domain superfamily
    Homologous_superfamily IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pde8a No data available
    MARKER RELATIONSHIPS
    pde8a Encodes: [cDNA] MGC:158458 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080627 (1)
    Genomic GenBank:CABZ01064535 (1) 14424 bp
    Polypeptide UniProtKB:A1L1W3 (1) 817 aa
    Sequence Information (all 14)
    ORTHOLOGY for pde8a ( Chr: 18 )
    CITATIONS (14)